Staphylococcus aureus Panton-Valentine Leukocidin Is a Very Potent Cytotoxic Factor for Human Neutrophils

The role of the pore-forming Staphylococcus aureus toxin Panton-Valentine leukocidin (PVL) in severe necrotizing diseases is debated due to conflicting data from epidemiological studies of community-associated methicillin-resistant S. aureus (CA-MRSA) infections and various murine disease-models. In...

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Main Authors: Löffler, Bettina, Hussain, Muzaffar, Grundmeier, Matthias, Brück, Michaela, Holzinger, Dirk, Varga, Georg, Roth, Johannes, Kahl, Barbara C., Proctor, Richard A., Peters, Georg
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798753/
https://ncbi.nlm.nih.gov/pubmed/20072612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000715
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