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Importance of the Collagen Adhesin Ace in Pathogenesis and Protection against Enterococcus faecalis Experimental Endocarditis

Ace is an adhesin to collagen from Enterococcus faecalis expressed conditionally after growth in serum or in the presence of collagen. Here, we generated an ace deletion mutant and showed that it was significantly attenuated versus wild-type OG1RF in a mixed infection rat endocarditis model (P<0....

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Main Authors: Singh, Kavindra V., Nallapareddy, Sreedhar R., Sillanpää, Jouko, Murray, Barbara E.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798748/
https://ncbi.nlm.nih.gov/pubmed/20072611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000716
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