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Putting the brakes on BTLA in T cell–mediated cancer immunotherapy

Attenuating coinhibitory molecules for the treatment of cancer is gaining a great deal of attention as a strategy for immunotherapy. The B and T lymphocyte attenuator (BTLA, CD272) is a novel coinhibitory molecule structurally and functionally related to CTLA-4 and PD-1. A study in this issue of the...

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Autors principals: Paulos, Chrystal M., June, Carl H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798708/
https://ncbi.nlm.nih.gov/pubmed/20038807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41811
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