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Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice

Adipose tissue inflammation is linked to the pathogenesis of insulin resistance. In addition to exerting death-promoting effects, the death receptor Fas (also known as CD95) can activate inflammatory pathways in several cell lines and tissues, although little is known about the metabolic consequence...

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Detalhes bibliográficos
Main Authors: Wueest, Stephan, Rapold, Reto A., Schumann, Desiree M., Rytka, Julia M., Schildknecht, Anita, Nov, Ori, Chervonsky, Alexander V., Rudich, Assaf, Schoenle, Eugen J., Donath, Marc Y., Konrad, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798678/
https://ncbi.nlm.nih.gov/pubmed/19955656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38388
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