Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling

The epigenetic silencing of tumor suppressor genes is a crucial event during carcinogenesis and metastasis. Here, in a human genome-wide survey, we identified scavenger receptor class A, member 5 (SCARA5) as a candidate tumor suppressor gene located on chromosome 8p. We found that SCARA5 expression...

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Bibliografiske detaljer
Main Authors: Huang, Jian, Zheng, Da-Li, Qin, Feng-Song, Cheng, Na, Chen, Hui, Wan, Bing-Bing, Wang, Yu-Ping, Xiao, Hua-Sheng, Han, Ze-Guang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798676/
https://ncbi.nlm.nih.gov/pubmed/20038795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38012
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