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Human apolipoprotein B (apoB) mRNA: identification of two distinct apoB mRNAs, an mRNA with the apoB-100 sequence and an apoB mRNA containing a premature in-frame translational stop codon, in both liver and intestine.

Human apolipoprotein B (apoB) is present in plasma as two separate isoproteins, designated apoB-100 (512 kDa) and apoB-48 (250 kDa). ApoB is encoded by a single gene on chromosome 2, and a single nuclear mRNA is edited and processed into two separate apoB mRNAs. A 14.1-kilobase apoB mRNA codes for a...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Higuchi, K, Hospattankar, A V, Law, S W, Meglin, N, Cortright, J, Brewer, H B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279861/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2450346/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.6.1772
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