Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter.

Okadaic acid is a polyether compound of a C38 fatty acid, isolated from a black sponge, Halichondria okadai. Previous studies showed that okadaic acid is a skin irritant and induces ornithine decarboxylase (OrnDCase; 3-hydroxyl-L-glutamate 1-carboxy-lyase, EC 4.1.1.17) in mouse skin 4 hr after its a...

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Autores principales: Suganuma, M, Fujiki, H, Suguri, H, Yoshizawa, S, Hirota, M, Nakayasu, M, Ojika, M, Wakamatsu, K, Yamada, K, Sugimura, T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1988
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC279860/
https://ncbi.nlm.nih.gov/pubmed/3126494
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