Molecular cloning and nucleotide sequence for the complete coding region of human UMP synthase.
The last two steps in the de novo biosynthesis of UMP are catalyzed by orotate phosphoribosyltransferase (OPRT; orotidine-5'-phosphate:pyrophosphate phosphoribosyltransferase; EC 2.4.2.10) and orotidine-5'-monophosphate decarboxylase (orotidine-5'-phosphate carboxy-lyase; EC 4.1.1.23). In mammals th...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1988
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279857/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3279416/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.6.1754 |
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