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A Single Mutation in Enzyme I of the Sugar Phosphotransferase System Confers Penicillin Tolerance to Streptococcus gordonii

Tolerance is a poorly understood phenomenon that allows bacteria exposed to a bactericidal antibiotic to stop their growth and withstand drug-induced killing. This survival ability has been implicated in antibiotic treatment failures. Here, we describe a single nucleotide mutation (tol1) in a tolera...

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Библиографические подробности
Главные авторы: Bizzini, A., Entenza, J. M., Michielin, O., Arnold, I., Erni, B., Moreillon, P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798540/
https://ncbi.nlm.nih.gov/pubmed/19858257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00699-09
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