Dose Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Nemonoxacin (TG-873870), a Novel Potent Broad-Spectrum Nonfluorinated Quinolone, in Healthy Volunteers

Nemonoxacin (TG-873870) is a novel nonfluorinated quinolone with potent broad-spectrum activity against Gram-positive and Gram-negative pathogens, including methicillin-resistant Staphylococcus aureus, penicillin- and quinolone-resistant Streptococcus pneumoniae, and vancomycin-intermediate and vanc...

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Detalhes bibliográficos
Main Authors: Lin, Luke, Chang, Li-Wen, Tsai, Cheng-Yuan, Hsu, Ching-Hung, Chung, David T., Aronstein, William S., Ajayi, Funmi, Kuzmak, Barbara, Lyon, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798534/
https://ncbi.nlm.nih.gov/pubmed/19884368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00682-09
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