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Patients with Long-Term Oral Carriage Harbor High-Persister Mutants of Candida albicans

Fungal biofilms produce a small number of persister cells which can tolerate high concentrations of fungicidal agents. Persisters form upon attachment to a surface, an important step in the pathogenesis of Candida strains. The periodic application of antimicrobial agents may select for strains with...

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Detalhes bibliográficos
Main Authors: LaFleur, Michael D., Qi, Qingguo, Lewis, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798516/
https://ncbi.nlm.nih.gov/pubmed/19841146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00860-09
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