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CUCU Modification of mRNA Promotes Decapping and Transcript Degradation in Aspergillus nidulans

In eukaryotes, mRNA decay is generally initiated by the shortening of the poly(A) tail mediated by the major deadenylase complex Ccr4-Caf1-Not. The deadenylated transcript is then rapidly degraded, primarily via the decapping-dependent pathway. Here we report that in Aspergillus nidulans both the Ca...

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Detalles Bibliográficos
Main Authors: Morozov, Igor Y., Jones, Meriel G., Razak, Ammar Abdul, Rigden, Daniel J., Caddick, Mark X.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798463/
https://ncbi.nlm.nih.gov/pubmed/19901075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00997-09
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