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Interaction between Ebola Virus Glycoprotein and Host Toll-Like Receptor 4 Leads to Induction of Proinflammatory Cytokines and SOCS1

Ebola virus initially targets monocytes and macrophages, which can lead to the release of proinflammatory cytokines and chemokines. These inflammatory cytokines are thought to contribute to the development of circulatory shock seen in fatal Ebola virus infections. Here we report that host Toll-like...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Okumura, Atsushi, Pitha, Paula M., Yoshimura, Akihiko, Harty, Ronald N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798428/
https://ncbi.nlm.nih.gov/pubmed/19846529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01462-09
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