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Interaction between Ebola Virus Glycoprotein and Host Toll-Like Receptor 4 Leads to Induction of Proinflammatory Cytokines and SOCS1

Ebola virus initially targets monocytes and macrophages, which can lead to the release of proinflammatory cytokines and chemokines. These inflammatory cytokines are thought to contribute to the development of circulatory shock seen in fatal Ebola virus infections. Here we report that host Toll-like...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Okumura, Atsushi, Pitha, Paula M., Yoshimura, Akihiko, Harty, Ronald N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798428/
https://ncbi.nlm.nih.gov/pubmed/19846529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01462-09
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