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Both RIG-I and MDA5 RNA Helicases Contribute to the Induction of Alpha/Beta Interferon in Measles Virus-Infected Human Cells

Measles virus (MV), a member of the family Paramyxoviridae, is a nonsegmented negative-strand RNA virus. The RNA helicases retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5) are differentially involved in the detection of cytoplasmic viral RNAs and induction...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ikegame, Satoshi, Takeda, Makoto, Ohno, Shinji, Nakatsu, Yuichiro, Nakanishi, Yoichi, Yanagi, Yusuke
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798399/
https://ncbi.nlm.nih.gov/pubmed/19846522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01690-09
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