Integrity of the Early Secretory Pathway Promotes, but Is Not Required for, Severe Acute Respiratory Syndrome Coronavirus RNA Synthesis and Virus-Induced Remodeling of Endoplasmic Reticulum Membranes

To accommodate its RNA synthesis in the infected cell, severe acute respiratory syndrome coronavirus (SARS-CoV) induces a cytoplasmic reticulovesicular network (RVN) that is derived from endoplasmic reticulum (ER) membranes. We set out to investigate how the early secretory pathway interacts with th...

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Detalhes bibliográficos
Main Authors: Knoops, Kèvin, Swett-Tapia, Cindy, van den Worm, Sjoerd H. E., te Velthuis, Aartjan J. W., Koster, Abraham J., Mommaas, A. Mieke, Snijder, Eric J., Kikkert, Marjolein
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798390/
https://ncbi.nlm.nih.gov/pubmed/19889777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01826-09
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