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Insulin-Degrading Enzyme Binds to the Nonglycosylated Precursor of Varicella-Zoster Virus gE Protein Found in the Endoplasmic Reticulum

Insulin degradation enzyme (IDE) is a 110-kDa zinc metalloprotease found in the cytosol of all cells. IDE degrades insulin and a variety of small proteins including amyloid-β. Recently, IDE has been proposed as the receptor for varicella-zoster virus (VZV) attachment. During our reassessment, some o...

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Detalhes bibliográficos
Main Authors: Carpenter, J. E., Jackson, W., de Souza, G. A., Haarr, L., Grose, C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798375/
https://ncbi.nlm.nih.gov/pubmed/19864391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01801-09
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