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Differential Impact of Immune Escape Mutations G145R and P120T on the Replication of Lamivudine-Resistant Hepatitis B Virus e Antigen-Positive and -Negative Strains

Immune escape variants of the hepatitis B virus (HBV) represent an emerging clinical challenge, because they can be associated with vaccine escape, HBV reactivation, and failure of diagnostic tests. Recent data suggest a preferential selection of immune escape mutants in distinct peripheral blood le...

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Autors principals: Amini-Bavil-Olyaee, Samad, Vucur, Mihael, Luedde, Tom, Trautwein, Christian, Tacke, Frank
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798356/
https://ncbi.nlm.nih.gov/pubmed/19889778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01796-09
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