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Blimp-1-Dependent Plasma Cell Differentiation Is Required for Efficient Maintenance of Murine Gammaherpesvirus Latency and Antiviral Antibody Responses

Recent evidence from the study of Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus supports a model in which terminal differentiation of B cells to plasma cells leads to virus reactivation. Here we address the role of Blimp-1, the master transcriptional regulator of plasma cell di...

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Detalhes bibliográficos
Main Authors: Siegel, Andrea M., Rangaswamy, Udaya Shankari, Napier, Ruth J., Speck, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798350/
https://ncbi.nlm.nih.gov/pubmed/19889763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01306-09
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