Characterization of Lassa Virus Glycoprotein Oligomerization and Influence of Cholesterol on Virus Replication

Mature glycoprotein spikes are inserted in the Lassa virus envelope and consist of the distal subunit GP-1, the transmembrane-spanning subunit GP-2, and the signal peptide, which originate from the precursor glycoprotein pre-GP-C by proteolytic processing. In this study, we analyzed the oligomeric s...

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Bibliographic Details
Main Authors: Schlie, Katrin, Maisa, Anna, Lennartz, Frank, Ströher, Ute, Garten, Wolfgang, Strecker, Thomas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798336/
https://ncbi.nlm.nih.gov/pubmed/19889753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02039-09
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