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Activation of the S-Phase Checkpoint Inhibits Degradation of the F-Box Protein Dia2

A stable genome is critical to cell viability and proliferation. During DNA replication, the S-phase checkpoint pathway responds to replication stress. In budding yeast, the chromatin-bound F-box protein Dia2 is required to maintain genomic stability and may help replication complexes overcome sites...

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Detalhes bibliográficos
Main Authors: Kile, Andrew C., Koepp, Deanna M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798289/
https://ncbi.nlm.nih.gov/pubmed/19858292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00612-09
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