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Activation of the S-Phase Checkpoint Inhibits Degradation of the F-Box Protein Dia2
A stable genome is critical to cell viability and proliferation. During DNA replication, the S-phase checkpoint pathway responds to replication stress. In budding yeast, the chromatin-bound F-box protein Dia2 is required to maintain genomic stability and may help replication complexes overcome sites...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology (ASM)
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798289/ https://ncbi.nlm.nih.gov/pubmed/19858292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00612-09 |
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