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Three-Dimensional Structure of Different Functional Forms of the Vibrio cholerae Hemolysin Oligomer: a Cryo-Electron Microscopic Study

Vibrio cholerae hemolysin (HlyA) is a 65-kDa water-soluble pore-forming toxin that causes lysis of eukaryotic cells by destroying selective permeability of the plasma membrane bilayer. The HlyA monomer self-assembles on the target cell surface to the more stable β-barrel amphipathic heptamer, which...

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Detalhes bibliográficos
Main Authors: Dutta, Somnath, Mazumdar, Budhaditya, Banerjee, Kalyan K., Ghosh, Amar N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798276/
https://ncbi.nlm.nih.gov/pubmed/19854900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00930-09
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