Metabolic Control of Virulence Genes in Brucella abortus: HutC Coordinates virB Expression and the Histidine Utilization Pathway by Direct Binding to Both Promoters

Type IV secretion systems (T4SS) are multicomponent machineries involved in the translocation of effector molecules across the bacterial cell envelope. The virB operon of Brucella abortus codes for a T4SS that is essential for virulence and intracellular multiplication of the bacterium in the host....

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Bibliographic Details
Main Authors: Sieira, Rodrigo, Arocena, Gastón M., Bukata, Lucas, Comerci, Diego J., Ugalde, Rodolfo A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Molecular Biology of Pathogens
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798258/
https://ncbi.nlm.nih.gov/pubmed/19854911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01124-09
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