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Hepatitis B synthetic immunogen comprised of nucleocapsid T-cell sites and an envelope B-cell epitope.

Previous studies located T-cell recognition of the nucleocapsid of the hepatitis B virus (HBcAg) to residues 120-140 in mice bearing the H-2s or H-2b haplotypes. Herein, we demonstrate that B10.S (H-2s) and B10 (H-2b) H-2 congenic strains recognize distinct T-cell sites within the p120-140 (a synthe...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Milich, D R, Hughes, J L, McLachlan, A, Thornton, G B, Moriarty, A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1988
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279823/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2449694/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.5.1610
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