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Burkholderia mallei Cluster 1 Type VI Secretion Mutants Exhibit Growth and Actin Polymerization Defects in RAW 264.7 Murine Macrophages

Burkholderia mallei is a facultative intracellular pathogen that causes severe disease in animals and humans. Recent studies have shown that the cluster 1 type VI secretion system (T6SS-1) expressed by this organism is essential for survival in a hamster model of glanders. To better understand the r...

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Detalhes bibliográficos
Main Authors: Burtnick, Mary N., DeShazer, David, Nair, Vinod, Gherardini, Frank C., Brett, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798217/
https://ncbi.nlm.nih.gov/pubmed/19884331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00985-09
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