Salmonella enterica Serovar Typhimurium trxA Mutants Are Protective against Virulent Challenge and Induce Less Inflammation than the Live-Attenuated Vaccine Strain SL3261

In Salmonella enterica serovar Typhimurium, trxA encodes thioredoxin 1, a small, soluble protein with disulfide reductase activity, which catalyzes thiol disulfide redox reactions in a variety of substrate proteins. Thioredoxins are involved as antioxidants in defense against oxidative stresses, suc...

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Detalhes bibliográficos
Main Authors: Peters, S. E., Paterson, G. K., Bandularatne, E. S. D., Northen, H. C., Pleasance, S., Willers, C., Wang, J., Foote, A. K., Constantino-Casas, F., Scase, T. J., Blacklaws, B. A., Bryant, C. E., Mastroeni, P., Charles, I. G., Maskell, D. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798184/
https://ncbi.nlm.nih.gov/pubmed/19884329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00768-09
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