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Clathrin-independent internalization of normal cellular prion protein in neuroblastoma cells is associated with the Arf6 pathway

To understand the role of clathrin-mediated endocytosis in the internalization of normal cellular prion protein (PrP(c)) in neuronal cells, N2a cells were depleted of clathrin by RNA interference. PrP(c) internalization via the constitutive endocytic pathway in the absence of Cu(2+) and the stimulat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kang, Young-Shin, Zhao, Xiaohong, Lovaas, Jenna, Eisenberg, Evan, Greene, Lois E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798124/
https://ncbi.nlm.nih.gov/pubmed/19843586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.046292
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