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Association of the G-463A Myeloperoxidase Gene Polymorphism with Renal Disease in African Americans with Systemic Lupus Erythematosus

OBJECTIVE: Myeloperoxidase (MPO) is an enzyme expressed in neutrophils that is involved in tissue damage in inflammatory renal diseases. A functional G to A single-nucleotide polymorphism (SNP) is present at position −463 of the MPO promoter region and is associated with altered MPO expression. We h...

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Detalhes bibliográficos
Main Authors: BOUALI, HENDA, NIETERT, PAUL, NOWLING, TAMARA M., PANDEY, JANARDAN, DOOLEY, MARY ANNE, COOPER, GLINDA, HARLEY, JOHN, KAMEN, DIANE L., OATES, JIM, GILKESON, GARY
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798120/
https://ncbi.nlm.nih.gov/pubmed/17896805
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