Dual-targeted Contrast Agent for US Assessment of Tumor Angiogenesis in Vivo(1)

PURPOSE: To develop and validate a dual-targeted ultrasonographic (US) imaging agent with microbubbles (MBs) that attaches to both vascular endothelial growth factor (VEGF) receptor 2 (VEGFR2) and α(v)β(3) integrin and to compare the US imaging signal obtained from dual-targeted MBs (MB(D)) with tha...

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Bibliographische Detailangaben
Hauptverfasser: Willmann, Jürgen K., Lutz, Amelie M., Paulmurugan, Ramasamy, Patel, Manishkumar R., Chu, Pauline, Rosenberg, Jarrett, Gambhir, Sanjiv S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Radiological Society of North America, Inc. 2008
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798094/
https://ncbi.nlm.nih.gov/pubmed/18710985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.2483072231
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