Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene.
Established REF52 cells (rat embryo fibroblasts) completely resist stable transformation by ras oncogenes, and simian virus 40 large tumor (T) antigen collaborates with ras to convert REF52 cells to tumorigenic state. A temperature-sensitive simian virus 40 large T antigen (encoded by tsA58) allowed...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1988
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279804/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2830621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.5.1519 |
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