Endpoints in Phase II trials for advanced non-small cell lung cancer

INTRODUCTION: We investigated the relationships between progression-free survival (PFS), response, confirmed response, and failure-free survival (FFS) with overall survival (OS) to assess their suitability as primary endpoints in phase II (P2) trials for advanced NSCLC. METHODS: Individual data of 2...

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Autori principali: Mandrekar, Sumithra J., Qi, Yingwei, Hillman, Shauna L., Allen Ziegler, Katie L., Reuter, Nicholas F., Rowland, Kendrith M., Kuross, Steven A., Marks, Randolph S., Schild, Steven E., Adjei, Alex A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798014/
https://ncbi.nlm.nih.gov/pubmed/19884856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3181c0a313
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