Polymorphisms in the Vitamin A Receptor and Innate Immunity Genes Influence the Antibody Response to Rubella Vaccination

BACKGROUND: Genetic polymorphisms play an important role in rubella vaccine-induced immunity. METHODS: We genotyped 714 healthy children after two age-appropriate doses of rubella-containing vaccine for 142 potential SNPs. RESULTS: Specific polymorphisms in the vitamin A receptor, RIG-I, TRIM5 and T...

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Main Authors: Ovsyannikova, Inna G., Haralambieva, Iana H., Dhiman, Neelam, O’Byrne, Megan M., Pankratz, V. Shane, Jacobson, Robert M., Poland, Gregory A.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798005/
https://ncbi.nlm.nih.gov/pubmed/20001730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/649588
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