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Pro12Ala Polymorphism in the PPARG Gene Contributes to the Development of Diabetic Nephropathy in Chinese Type 2 Diabetic Patients

OBJECTIVE: Oxidative stress is a major contributing factor in the development of diabetic nephropathy. Peroxisome proliferator–activated receptor γ heterozygous mice and Pro12Ala polymorphism in PPARG exhibited increased resistance to oxidative stress. Smoking increases the production of reactive ox...

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Detalhes bibliográficos
Main Authors: Liu, Limei, Zheng, Taishan, Wang, Feng, Wang, Niansong, Song, Yanyan, Li, Ming, Li, Lifang, Jiang, Jiamei, Zhao, Weijing
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797960/
https://ncbi.nlm.nih.gov/pubmed/19837787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc09-1258
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