Insulin Resistance Is Associated With Higher Intramyocellular Triglycerides in Type I but Not Type II Myocytes Concomitant With Higher Ceramide Content

OBJECTIVE: We tested the primary hypotheses that sphingolipid and diacylglycerol (DAG) content is higher within insulin-resistant muscle and that the association between intramyocellular triglycerides (IMTG) and insulin resistance is muscle fiber type specific. RESEARCH DESIGN AND METHODS: A nested...

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Hauptverfasser: Coen, Paul M., Dubé, John J., Amati, Francesca, Stefanovic-Racic, Maja, Ferrell, Robert E., Toledo, Frederico G.S., Goodpaster, Bret H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2010
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797948/
https://ncbi.nlm.nih.gov/pubmed/19833891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0988
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