Tpl2 Kinase Is Upregulated in Adipose Tissue in Obesity and May Mediate Interleukin-1β and Tumor Necrosis Factor-α Effects on Extracellular Signal–Regulated Kinase Activation and Lipolysis

OBJECTIVE: Activation of extracellular signal–regulated kinase-(ERK)-1/2 by cytokines in adipocytes is involved in the alterations of adipose tissue functions participating in insulin resistance. This study aims at identifying proteins regulating ERK1/2 activity, specifically in response to inflamma...

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Detalhes bibliográficos
Main Authors: Jager, Jennifer, Grémeaux, Thierry, Gonzalez, Teresa, Bonnafous, Stéphanie, Debard, Cyrille, Laville, Martine, Vidal, Hubert, Tran, Albert, Gual, Philippe, Le Marchand-Brustel, Yannick, Cormont, Mireille, Tanti, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797946/
https://ncbi.nlm.nih.gov/pubmed/19808894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0470
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