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Antigen-Specific Induction of Osteopontin Contributes to the Chronification of Allergic Contact Dermatitis
Allergic contact dermatitis is a T cell-mediated immune response, which in its relapsing chronic form is of high socioeconomic impact. The phosphoglycoprotein osteopontin (OPN) has chemotactic and Th1 cytokine functions and in various models is essential for robust T cell-mediated immunity. Here we...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797887/ https://ncbi.nlm.nih.gov/pubmed/20008129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090488 |
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