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Antigen-Specific Induction of Osteopontin Contributes to the Chronification of Allergic Contact Dermatitis

Allergic contact dermatitis is a T cell-mediated immune response, which in its relapsing chronic form is of high socioeconomic impact. The phosphoglycoprotein osteopontin (OPN) has chemotactic and Th1 cytokine functions and in various models is essential for robust T cell-mediated immunity. Here we...

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Detalhes bibliográficos
Main Authors: Seier, Anne M., Renkl, Andreas C., Schulz, Guido, Uebele, Tanja, Sindrilaru, Anca, Iben, Sebastian, Liaw, Lucy, Kon, Shigeyuki, Uede, Toshimitsu, Weiss, Johannes M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797887/
https://ncbi.nlm.nih.gov/pubmed/20008129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090488
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