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α2-Antiplasmin Is Associated with the Progression of Fibrosis

Systemic sclerosis results in tissue fibrosis due to the activation of fibroblasts and the ensuing overproduction of the extracellular matrix. We previously reported that the absence of α2-antiplasmin (α2AP) attenuated the process of dermal fibrosis; however, the detailed mechanism of how α2AP affec...

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Hlavní autoři: Kanno, Yosuke, Kawashita, Eri, Minamida, Misato, Kaneiwa, Aki, Okada, Kiyotaka, Ueshima, Shigeru, Matsuo, Osamu, Matsuno, Hiroyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797886/
https://ncbi.nlm.nih.gov/pubmed/20008146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090150
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