α2-Antiplasmin Is Associated with the Progression of Fibrosis

Systemic sclerosis results in tissue fibrosis due to the activation of fibroblasts and the ensuing overproduction of the extracellular matrix. We previously reported that the absence of α2-antiplasmin (α2AP) attenuated the process of dermal fibrosis; however, the detailed mechanism of how α2AP affec...

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Autors principals: Kanno, Yosuke, Kawashita, Eri, Minamida, Misato, Kaneiwa, Aki, Okada, Kiyotaka, Ueshima, Shigeru, Matsuo, Osamu, Matsuno, Hiroyuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797886/
https://ncbi.nlm.nih.gov/pubmed/20008146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090150
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