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N-acetylaspartic acid in cerebrospinal fluid of multiple sclerosis patients determined by gas-chromatography-mass spectrometry

BACKGROUND: Axonal degeneration is considered to play a major role in the development of clinical disability in multiple sclerosis (MS). N-AcetylAspartic Acid (NAA) is a neuron-specific marker constantly identified in MR-spectroscopy studies of the normal and MS brain. To our knowledge there are no...

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Main Authors: Jasperse, Bas, Jakobs, Cornelis, Eikelenboom, M. Judith, Dijkstra, Christine D., Uitdehaag, Bernard M. J., Barkhof, Frederik, Polman, Chris H., Teunissen, Charlotte E.
Formato: Artigo
Idioma:Inglês
Publicado em: Steinkopff-Verlag 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797839/
https://ncbi.nlm.nih.gov/pubmed/17415509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00415-006-0415-5
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