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Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes
Cortical GABAergic dysfunction may underlie the pathophysiology of psychiatric disorders, including schizophrenia. Here, we characterized a mouse strain in which the essential NR1 subunit of the NMDA receptor (NMDAR) was selectively eliminated in 40–50% of cortical and hippocampal interneurons in ea...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797836/ https://ncbi.nlm.nih.gov/pubmed/19915563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2447 |
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