A replication study of the association between the IL12B promoter allele CTCTAA and susceptibility to cerebral malaria in Thai population

BACKGROUND: Interleukin-12 (IL-12), a heterodimeric cytokine composed of p35 and p40 subunits, has been thought to play an important role in the pathogenesis of malaria. The IL-12p40 subunit is encoded by the IL12B gene. An IL12B promoter allele, CTCTAA, at rs17860508 has been reported to be associa...

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Main Authors: Naka, Izumi, Patarapotikul, Jintana, Tokunaga, Katsushi, Hananantachai, Hathairad, Tsuchiya, Naoyuki, Ohashi, Jun
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797809/
https://ncbi.nlm.nih.gov/pubmed/20003322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-8-290
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