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Anti-CD3 antibody decreases inflammation and improves outcome in a murine model of Pneumocystis pneumonia
The T cell-mediated immune response elicited by Pneumocystis plays a key role in pulmonary damage and dysfunction during Pneumocystis pneumonia (PcP). Mice depleted of CD4(+) and CD8(+) T cells prior to infection are markedly protected from PcP-related respiratory deficit and death despite progressi...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797573/ https://ncbi.nlm.nih.gov/pubmed/19949093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901864 |
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