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Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study

BACKGROUND: The xenobiotic transporters, Multidrug Resistance 1 (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) may restrict intestinal absorption of various carcinogens, including heterocyclic amines (HCA) and polycyclic aromatic hydrocarbons (PAH). Cyclooxygenase-2 (COX-2) derived p...

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Detalhes bibliográficos
Main Authors: Andersen, Vibeke, Østergaard, Mette, Christensen, Jane, Overvad, Kim, Tjønneland, Anne, Vogel, Ulla
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797527/
https://ncbi.nlm.nih.gov/pubmed/19930591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-407
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