Transformation of thebaine to oripavine, codeine, and morphine by rat liver, kidney, and brain microsomes.
Thebaine, an intermediate of morphine biosynthesis in the poppy plant, Papaver somniferum, was transformed to oripavine, codeine, and morphine by rat liver, kidney, and brain microsomes in the presence of an NADPH-generating system. The formation of morphine, codeine, and oripavine was identified by...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1988
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279748/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3422490/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.4.1267 |
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