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The Inhibitory Effect of Ghrelin on Sepsis Induced Inflammation is Mediated by the MAPK phosphatase-1

Hepatocellular dysfunction occurs early in sepsis and this appears to be caused by Kupffer cell derived TNF-α production from the liver as a result of the increased release of the sympathetic neurotransmitter, norepinephrine, from the gut. Ghrelin, a novel stomach-derived peptide, is downregulated i...

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書誌詳細
主要な著者: Jacob, Asha, Rajan, Derry, Pathickal, Betsy, Balouch, Imran, Hartman, Adam, Wu, Rongqian, Zhou, Mian, Wang, Ping
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797446/
https://ncbi.nlm.nih.gov/pubmed/19956915
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