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The Inhibitory Effect of Ghrelin on Sepsis Induced Inflammation is Mediated by the MAPK phosphatase-1
Hepatocellular dysfunction occurs early in sepsis and this appears to be caused by Kupffer cell derived TNF-α production from the liver as a result of the increased release of the sympathetic neurotransmitter, norepinephrine, from the gut. Ghrelin, a novel stomach-derived peptide, is downregulated i...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797446/ https://ncbi.nlm.nih.gov/pubmed/19956915 |
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