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Synthetic peptides corresponding to protective epitopes of Escherichia coli digalactoside-binding pilin prevent infection in a murine pyelonephritis model.

Synthetic peptides corresponding to five segments of a globoside (Gal-Gal)-binding pilin sequence [residues 5-12 (R5-12), R65-75, R93-104, R103-116, and R131-143], cyanogen bromide fragment II (CNBr-II, R53-163), and purified, intact Gal-Gal pili were prepared as vaccines and tested for their effica...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Schmidt, M A, O'Hanley, P, Lark, D, Schoolnik, G K
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279744/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2448796/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.4.1247
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