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Transglutaminase 2, a Novel Regulator of Eicosanoid Production in Asthma Revealed by Genome-Wide Expression Profiling of Distinct Asthma Phenotypes

BACKGROUND: A frequent manifestation of asthma, exercise-induced bronchoconstriction (EIB), occurs in 30–50% of asthmatics and is characterized by increased release of inflammatory eicosanoids. The objective of this study was to identify genes differentially expressed in EIB and to understand the fu...

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Main Authors: Hallstrand, Teal S., Wurfel, Mark M., Lai, Ying, Ni, Zhanglin, Gelb, Michael H., Altemeier, William A., Beyer, Richard P., Aitken, Moira L., Henderson, William R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797392/
https://ncbi.nlm.nih.gov/pubmed/20052409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008583
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