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Antigen presentation to HLA class II-restricted measles virus-specific T-cell clones can occur in the absence of the invariant chain.

A human fibroblast line expressing HLA-DR1 antigen on its surface was generated by transfection with DR alpha and DR beta cDNAs. Expression of the invariant chain gene was not detectable in the transfected fibroblasts and was not induced by infection with measles virus. Lysis of measles virus-infect...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sekaly, R P, Jacobson, S, Richert, J R, Tonnelle, C, McFarland, H F, Long, E O
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279736/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3257576/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.4.1209
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