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A Strategy for Eliciting Antibodies against Cryptic, Conserved, Conformationally Dependent Epitopes of HIV Envelope Glycoprotein

BACKGROUND: Novel strategies are needed for the elicitation of broadly neutralizing antibodies to the HIV envelope glycoprotein, gp120. Experimental evidence suggests that combinations of antibodies that are broadly neutralizing in vitro may protect against challenge with HIV in nonhuman primates, a...

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Detalles Bibliográficos
Main Authors: Kelker, Hanna C., Itri, Vincenza R., Valentine, Fred T.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797330/
https://ncbi.nlm.nih.gov/pubmed/20052405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008555
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