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A Strategy for Eliciting Antibodies against Cryptic, Conserved, Conformationally Dependent Epitopes of HIV Envelope Glycoprotein

BACKGROUND: Novel strategies are needed for the elicitation of broadly neutralizing antibodies to the HIV envelope glycoprotein, gp120. Experimental evidence suggests that combinations of antibodies that are broadly neutralizing in vitro may protect against challenge with HIV in nonhuman primates, a...

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Main Authors: Kelker, Hanna C., Itri, Vincenza R., Valentine, Fred T.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797330/
https://ncbi.nlm.nih.gov/pubmed/20052405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008555
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