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X-ray Crystal Structure of Michaelis Complex of Aldoxime Dehydratase

Aldoxime dehydratase (Oxd) catalyzes the dehydration of aldoximes (R–CH=N–OH) to their corresponding nitrile (R–C [Image: see text] N). Oxd is a heme-containing enzyme that catalyzes the dehydration reaction as its physiological function. We have determined the first two structures of Oxd: the subst...

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Autori principali: Sawai, Hitomi, Sugimoto, Hiroshi, Kato, Yasuo, Asano, Yasuhisa, Shiro, Yoshitsugu, Aono, Shigetoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797279/
https://ncbi.nlm.nih.gov/pubmed/19740758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018762
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